Can You Take Ozempic While Pregnant?
Ozempic (semaglutide) has skyrocketed in popularity for weight loss and type 2 diabetes management but, what happens when a woman becomes pregnant while taking it?
Whether you’re actively trying to conceive, unexpectedly pregnant, or planning for the future, the question of Ozempic and pregnancy is a critical one. Here’s what we know so far, straight from clinical guidelines, emerging research, and women who’ve lived through it.
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Can you take Ozempic during pregnancy?
Experts recommend stopping Ozempic at least two months before trying to conceive. It’s not considered safe during pregnancy due to lack of data and possible fetal risks observed in animal studies.
Why It Matters
Ozempic is part of a class of medications called GLP-1 receptor agonists, originally developed for blood sugar regulation. Over time, these medications have proven incredibly effective for weight loss and insulin sensitivity. But their role during pregnancy is still unclear—and likely risky.
“There’s simply not enough human data,” says Dr. Alana Michelson, an OB-GYN specializing in high-risk pregnancies. “What we do know from animal studies is that semaglutide may pose risks to fetal development, especially in the early stages.”
The FDA has categorized semaglutide as Category C: animal reproduction studies have shown adverse effects on the fetus, and there are no adequate human studies. For this reason, it’s not currently recommended for use during pregnancy.
Real Talk: What Women Are Saying
Julia, 36 found out she was pregnant while taking Ozempic for weight loss.
“I was only two months in and had just hit a good rhythm with my appetite. Then I missed a period. I stopped immediately, called my doctor, and held my breath. Thankfully, everything’s been okay so far, but I felt panicked.”
Dina, 29, was on Ozempic to manage PCOS-related insulin resistance.
“I didn’t plan to get pregnant, but I also didn’t realize I needed to stop the drug ahead of time. I had a miscarriage at 9 weeks. Was it related? My doctor said maybe not, but it’s a question I’ll always carry.”
These stories aren’t meant to scare you—they’re meant to highlight the importance of communication between women and their healthcare teams when using powerful medications like GLP-1s.
What Do the Guidelines Say?
According to Novo Nordisk, the manufacturer of Ozempic:
- Women of childbearing age should use contraception while on Ozempic.
- If a woman plans to conceive, Ozempic should be discontinued at least two months in advance due to its long half-life.
- The drug should not be used during pregnancy or breastfeeding.
The American College of Obstetricians and Gynecologists (ACOG) similarly recommends avoiding non-essential medications during pregnancy and prioritizing those with established safety profiles.
What About GLP-1s and Fertility?
Interestingly, some women report improved ovulation while on Ozempic, particularly those with PCOS. However, that can increase the chance of unexpected pregnancy—especially if you’ve been told conception might be difficult.
Be mindful: weight loss, insulin sensitivity, and hormonal changes can increase fertility without warning.
Alternatives During Pregnancy
If you were prescribed Ozempic for type 2 diabetes or insulin resistance, your doctor might switch you to:
- Insulin: A well-established, safe option during pregnancy.
- Metformin: Often used for PCOS and gestational diabetes, though not as effective for weight loss.
- Diet & lifestyle management: With extra focus on blood sugar control.
If you were using Ozempic purely for weight loss, pregnancy is not the time for weight management. Nutritional support, prenatal vitamins, and guidance from a registered dietitian are more appropriate tools during this time.
Quick Tip Box
Thinking About Pregnancy?
If you’re on Ozempic and planning to conceive, make a preconception plan with your doctor. You’ll likely need to stop the drug two months prior, adjust your nutrition, and possibly monitor hormone levels more closely.
Bottom Line
Ozempic and pregnancy don’t mix well. While the science is still evolving, current guidance is clear: stop semaglutide before trying to conceive and avoid using it during pregnancy. For women who accidentally conceive while on Ozempic, consult your doctor immediately and prepare for more careful monitoring.
The emotional toll of an unexpected pregnancy or miscarriage is real and deserves space in this conversation. If you’re feeling anxious or overwhelmed, reach out. Your health journey deserves clarity, compassion, and evidence-based care.
Suggested Reads
More from Healthy Living Magazine
- What Is Semaglutide? A Simple Guide
- What Doctors Really Think About GLP-1 Drugs
- Wegovy vs Ozempic: What’s the Difference?
Additional Resources
Olivia Davis
Olivia brings smart, simple ideas to everyday life — helping you live better with less effort.
