Sage, the New Alzheimer’s Hope

Sprinkle your food with the herb to enhance cognitive performance

Sage

Sage

A study from the Journal of Clinical Pharmacology and Therapy finds clinical evidence for sage’s effectiveness in mild to moderate AD.

The study used 60 drops/day in patients with mild to moderate AD over a 4-month period. Some received the sage but others placebo.

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At 4 months, the sage extract “produced a significant better outcome on cognitive functions than placebo,” the study found. “There were no significant differences in the two groups in terms of observed side-effects except agitation that appears to be more frequent in the placebo group. The results of this study indicate the efficacy of S. officinalis extract in the management of mild to moderate Alzheimer’s disease. Moreover, S. officinalis may well reduce agitation of patients…”

A second published report from CNS Neuroscience & Therapeutics notes that “S. officinalis and S. lavandulaefolia [lavender] exert beneficial effects by enhancing cognitive performance both in healthy subjects and patients with dementia or cognitive impairment and is safe for this indication.”

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Use fresh or dried leaves, sparingly. Sage goes well with salad, pork, beef, duck and chicken, and any fatty meats in particular. In Italian cuisine it is commonly chopped, mixed with melted butter and served stirred into pasta or gnocchi.

Reference Akhondzadeh S, Noroozian M, Mohammadi M, Ohadinia S, Jamshidi AH, Khani M. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther. 2003 Feb;28(1):53-9. Miroddi M, Navarra M, Quattropani MC, Calapai F, Gangemi S, Calapai G.Systematic review of clinical trials assessing pharmacological properties of Salvia species on memory, cognitive impairment and Alzheimer's disease. CNS Neurosci Ther. 2014 Jun;20(6):485-95. doi: 10.1111/cns.12270. Epub 2014 Apr 10.
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